Eicosanoids

   I. Background
      A. arachidonic acid (AA)
         1. phospholipase A2
      B. paracrine

  II. Prostaglandins
      A. History
      B. Description
      C. Function
      D. cyclooxygenase
         1. prostaglandin H2  (PGH2)
      E. Blocking cyclooxygenase
         1. cox 1
         2. cox 2
         3. aspirin
         4. cox 2 inhibitors

 III. Thromboxanes
      A. Description
      B. Function
      C. Synthesis
         1. thromboxane synthase

  IV. Prostacyclins
      A. Description
      B. Function
      C. Synthesis
         1. prostacyclin synthase

   V. Leukotrienes
      A. Description
      B. Function
      C. Synthesis
         1. leukotriene synthase
      D. Actions