electron ttansport chain

   I. Overview
      A. ATP needed
         1. oxidative phosphorylation
      B. protein & cofactor complexes
      C. Historical
         1. chemiosmotic theory
      D. Protonmotive Force
      E. Equation / Pathway
      F. Electron flow
         1. redox centers
      G. Location & Components

  II. Complex I
      A. Substrates
      B. Bound Cofactors
      C. Structure
      D. Reactions
         a. ubiquinone

 III. Complex II
      A. Substrates
      B. Bound cofactors
      C. Structure
      D. Reactions

  IV. Complex III
      A. Substrates
      B. Bound cofactors
         1. cytochromes
      C. Structure
      D. Reactions
         1. Q cycling

   V. Complex IV
      A. Substrates
      B. Bound cofactors
      C. Structure
      D. Reactions

  VI. Complex V
      A. Structure
         1.  F1 - alpha3 beta3 gamma delta epsioln
         2.  F0 - a1 b2 c10-14
      B. Reactions
         1. passage of H+s
         2. rotation of c and gamma
            a. conformations of F1
               1) loose
               2) tight
               3) open
               3.  binding-change mechanism

 VII. Transport
      A. ATP synthasome
         1. adenine nucleotide translocase
         2. phosphate translocase
      B. NADH
         1. malate-aspartate shuttle
         2. glycerol 3-P shuttle