Gluconeogenesis

   I. Background
      A. Definition
      B. Why
      C. Where
      D. Precursors

  II. Overview
      A. E requirements
      B. Reactions

 III. The 3 Crucial steps
      A. Pyruvate -> PEP 
         1. Pyruvate carboxylase
            a. Structure
               1) biotin
               2) active sites
            b. Rxn
            c. Control
            d. Compartmentalization
         2. PEPCK
            a. Structure
            b. Rxn
            c. Control
         3. Notes
      B. FBPase-1
         1. Cofactors
         2. Rxn
         3. Control
      C. Glucose 6-phosphatase
         1. Rxn
         2. Species & Cell type
         3. Location

  IV. Precursors
      A. lactic acid
      B. aas
      C. glycerol
      D. Others

   V. Cost