Translation         Chapter 7B

   I. Sets of Three
      A. Translation
      B. Genetic code
         1. codon
      C. Reading frames

  II. Transfer RNA
      A. tRNAs
         1. quantity
               1) wobble
         2. structure
            a. cloverleaf
            b. anticodon
      B. Aminoacyl-tRNA synthetases
         1. activated
         2. proofreading
      C. Initiation tRNA
         1. AUG
         2. tRNAiMet

 III. Ribosomes
      A. Structure
         1. rate
      B. rRNAs
         1. svedberg
         2. Pro
         3. Euk
      C. Initiation
         1. prokaryotic
            a. Shine-Dalgarno
         2. eukaryotic
            a. eIF2-GTP
            b. eIF5
               1) 43S preinitiation complex
            c. eIF4
            d. eIF5B-GTP
      D. Elongation
            a. elongation factors
         1. entry of aminoacyl-tRNA
            a. EF1a-GTP
         2. GTP hydrolysis
         3. peptidyltransferase reaction
         4. translocation
            a. EF2-GTP
      E. Termination
            a. stop codons
            b. release factors
         1. eRF1
         2. eRF3-GTP
         3. ABCE1
      F. Polysomes
      G. Protein synthesis antibiotics

  IV. Protein Degradation
      A. Why degrade
      B. How degrade
         1. lysosomes
         2. cytoplasmic
            a. ubiquitin
            b. proteasomes